lobe sciences ltd. (CSE: LOBE,OTC:LOBEF) (OTCQB: LOBEF) (FSE: LOBE.F) (‘Lobe Sciences’ or the ‘Company’) a clinical stage biopharmaceutical company focused on developing products to treat diseases with significant unmet medical needs is pleased to announce its participation in the upcoming ArcStone-Kingswood Growth Summit in Toronto, taking place at the St. Regis Toronto on September 18, 2025. Dr. Frederick D Sancilio, CEO of lobe sciences ltd. will be presenting the company’s recent milestones and future growth strategy.

The ArcStone-Kingswood Growth Summit will be hosting over 20 companies and a curated group of investors for a full day of pre-arranged, targeted 1-on-1 meetings, panel discussions and networking opportunities.

Alongside the schedule of pre-booked meetings matching investors with appropriate projects, the conference program will provide amble opportunities to mix and mingle with the industry professionals and catch up on key industry developments.

Interested investors who would like to attend the ArcStone-Kingswood Growth Summit can register to request for a free invitation here.

About ArcStone Securities and Investments Corp.

ArcStone Securities and Investments Corp. is a diversified financial services firm with offices in Toronto and New York. Our firm specializes in providing bespoke solutions to mid-market companies worldwide, with a particular focus on cross-border transactions between Canada and the United States. Our partnership with Kingswood US enhances our ability to offer a full spectrum of financial services to our clients.

About Kingswood US

Kingswood US is a mid-market investment bank with a strong retail equity capital markets franchise and deep-rooted investment bank. The firm is dedicated to providing comprehensive financial services, including investment banking, wealth management, and capital raising, to clients across the United States.

About lobe sciences ltd.

Lobe Sciences Ltd. is a clinical stage biopharmaceutical company focused on developing novel therapies for rare neurological and hematological conditions. The company operates through two subsidiaries:

• Altemia, Inc. is addressing sickle cell disease with two complementary assets: a medical food currently in early-stage distribution, and S-100, a patent-pending therapeutic candidate designed to treat the underlying pathology of the disease.

Lobe’s pipeline is differentiated by intellectual property, clinical momentum, and a strategic focus on high-value, underserved markets.

To view the source version of this press release, please visit https://www.newsfilecorp.com/release/265683

(TheNewswire)

Vancouver, British Columbia TheNewswire – September 15th, 2025 Prismo Metals Inc. (the ‘ Company ‘ ) (CSE: PRIZ,OTC:PMOMF) (OTCQB: PMOMF) is pleased to report that its exploration team has identified porphyry style mineralization at its Silver King project located outside the town of Superior in Arizona. Given the proximity of the nearby Resolution Copper deposit (a joint venture between Rio Tinto and BHP), the team is excited about the potential of this same style of mineralization identified at surface within the eastern portion of our claim.

‘ This region is world-class for porphyry systems and base and precious metals, and we believe there is significant untapped potential. Our recent field work at the Silver King mine was successful in identifying several exploration targets apart from the historic silver mine deposit including polymetallic veins, manto replacements and a strongly altered intrusion with stockwork quartz-pyrite veining. Identifying this porphyry style mineralization on the claim block is a very positive development ,’ said Dr. Craig Gibson , Chief Exploration Officer.

Figure 1 . Map showing Silver King project and nearby mineral deposits.

The Silver King deposit is located three kilometers from the Resolution Copper deposit and the high-grade Magma mine, a former copper and silver producer, located 0.6 to 1.5 kilometers to the southwest Mineralization at Silver King is hosted by the same rock sequence that hosts those two deposits but is exposed at surface and is not covered by the thick sequence of unmineralized volcanic rocks that covers Resolution Copper. From 1911 to 1996 the Magma mine was developed on veins and replacement deposits in the Paleozoic and Precambrian strata and intrusive rocks, producing approximately 27.6 million short tons of ore averaging about 4.9% copper with important quantities of zinc, gold (689K oz) and silver (34.3M oz) (Briggs, 2015), eventually leading to the discovery of the nearby Resolution copper deposit (Fig. 1).

M ineralization similar to that at the Magma mine is exposed in several historic mine workings with abundant oxide copper minerals, mainly malachite, which were developed along a northeast dipping limestone horizon near the contact with a quartz diorite intrusion and quartzite along the same structural and stratigraphic trend of the Magma mine. The largest occurrence, at the Black Diamond mine in the eastern portion of the claim block, was developed on a large outcrop of abundant specular hematite and malachite replacing a limestone bed (Fig. 2) .

Additionally, an erosional window in a regional quartz diorite has exposed a felsic intrusion to the east of the Silver King workings that was identified in historical records and now confirmed by Prismo geologists.  This felsic intrusion, previously described as a breccia pipe, is characterized by very strong stockwork quartz-pyrite veining in a quartz-sericite altered host rock. This target contains anomalous metal values in soil samples analyzed with the XRF. According to historical reports it has high salinity fluid inclusions typical of a porphyry system, providing evidence for porphyry mineralization on the Silver King claim package.

Figure 2 . Geologic and land map of the Silver King project showing newly described veins in magenta (Ag-Pb-Zn) and green (Cu-Ag) and replacement mineralization in red. The strongly altered intrusion with stock work quartz-pyrite veining is indicated by the crosshatch.

‘Much of the focus of the exploration program to date consisted of a property wide survey of historic mines and prospects surrounding the Silver King workings, ‘ said Gordon Aldcorn, President of Prismo .

‘ The exploration work has resulted in the identification of several mineralized occurrences on the property, including veins in the vicinity of the Silver King mine, and replacement and skarn mineralization in limestone units of the sedimentary sequence near the contact.’

Part of the initial exploration program consisted of a reconnaissance survey of the geology and mineral occurrences as well as a geochemical and alteration mineral survey around the surface expression of the Silver King deposit and a second separate target to the east.

The geochemical survey used a handheld XRF instrument to measure soil samples, and showed discrete anomalies for Cu, Ag, and Sb around the historic glory hole, with the copper geochemistry also associated with the ENE striking Cu bearing vein mentioned previously (Fig. 3). Twenty-nine samples have been submitted to the lab, with an additional fifteen samples from the Ripsey mine.

This initial phase of Prismo exploration on the Silver King project is already generating a better understanding of potential with new structures not fully uncovered in historical mining approaches. This work also helps qualify our upcoming drill program which is currently in the permitting stage and is anticipated to be advanced shortly.

Figure 3 . Soil geochemistry maps for Cu, Ag, and Sb from the Silver King mine.  Contours are from values measured in soils by a handheld XRF in the field, with ranges for Cu at 5,619 ppm to 12.5 ppm, Ag at 186 ppm to 1.3 ppm, and Sb at 300 ppm to 3.9 ppm.

Click Image To View Full Size

As previously reported in Primo’s news release of August 28, 2025, the Company geologists identified two previously undescribed veins in the area surrounding the historic glory hole developed on the original exposure of high-grade silver at the Silver King deposit.  Visual inspection and analysis with a handheld XRF show two distinct veins, one with abundant silver lead and zinc and the other with copper and silver values.

Figure 4 . Location of the Company’s projects within the Arizona Copper Belt

Qualified Person

Dr. Craig Gibson, PhD., CPG., a Qualified Person as defined by NI-43-01 regulations and Chief Exploration Officer and a director of the Company, has reviewed and approved the technical disclosures in this news release. The historic data presented in this press release was obtained from public sources, should be considered incomplete and is not qualified under NI 43-101, but is believed to be accurate. The Company has not verified the historical data presented and it cannot be relied upon, and it is being used solely to aid in exploration plans. References to mineralization at the Magma Mine and Resolution Copper deposit is not necessarily indicative of mineralization on the Silver King property.

1. (2) Briggs, D., 2015, Superior, Arizona: An old mining camp with many lives, Ariz. Geol Survey Contributed Report CR-15-D, 13p.

About the Silver King and Ripsey Mines

Discovered in 1875, the Silver King mine was one of Arizona’s most important historic producers, yielding nearly 6 million ounces of silver at grades of up to 61 oz/t.  The Silver King mine sits only 3 km from the main shaft of the Resolution Copper project — a joint venture between Rio Tinto and BHP and one of the world’s largest unmined copper deposits with an estimated copper resource of 1.787 billion metric tonnes at an average grade of 1.5% copper (1) . The unique land position is fully surrounded by Resolution Copper’s claim block, offering strategic upside. Selected samples from small-scale production in the late 1990s returned grades as high as 644 oz/t silver (18,250 g/t) and 0.53 oz/t gold (15 g/t), indicating that high-grade mineralization remains.

The Ripsey mine is a historic gold-silver-copper producer located about 20 km west of the Hot Breccia project. Historic mine workings consisting of tunnels and shafts on several levels were developed along a vein over about 400 meters of strike length and 160 meters vertically. A small tonnage of mineral was produced by the Optionor in the late 1990’s. Limited sampling by Dr. Craig Gibson from the mine workings has yielded 15.9 g/t gold and 275 g/t silver over 0.75 meters and 8.7 g/t gold, 181 g/t silver, 3% copper and 9% zinc over 1 meter.  No modern exploration has been carried out at the project, providing significant exploration upside and multiple drill targets.

About Prismo Metals Inc.

Prismo (CSE: PRIZ,OTC:PMOMF) is a mining exploration company focused on advancing its Silver King, Ripsey and Hot Breccia projects in Arizona and its Palos Verdes silver project in Mexico.

Please follow @PrismoMetals on , , , Instagram , and

Prismo Metals Inc.

1100 – 1111 Melville St., Vancouver, British Columbia V6E 3V6

Phone: (416) 361-0737

Contact:

Alain Lambert, Chief Executive Officer alain.lambert@prismometals.com

Gordon Aldcorn , President gordon.aldcorn@prismometals.com

Cautionary Note Regarding Forward-Looking Information

This release includes certain statements and information that may constitute forward-looking information within the meaning of applicable Canadian securities laws. Forward-looking statements relate to future events or future performance and reflect the expectations or beliefs of management of the Company regarding future events. Generally, forward-looking statements and information can be identified by the use of forward-looking terminology such as ‘ intends’ or ‘ anticipates ‘, or variations of such words and phrases or statements that certain actions, events or results ‘ may’, ‘ could’, ‘ should’, ‘ would’ or ‘ occur’. This information and these statements, referred to herein as ‘forward‐looking statements’, are not historical facts, are made as of the date of this news release and include without limitation, statements regarding discussions of future plans, estimates and forecasts and statements as to management’s expectations and intentions with respect to, among other things: the timing, costs and results of drilling at Hot Breccia.

These forward‐looking statements involve numerous risks and uncertainties, and actual results might differ materially from results suggested in any forward-looking statements. These risks and uncertainties include, among other things: delays in obtaining or failure to obtain appropriate funding to finance the exploration program at Silver King.

In making the forward-looking statements in this news release, the Company has applied several material assumptions, including without limitation, that: the ability to raise capital to fund the drilling campaign at Silver King and the timing of such drilling campaign.

Although management of the Company has attempted to identify important factors that could cause actual results to differ materially from those contained in forward-looking statements or forward-looking information, there may be other factors that cause results not to be as anticipated, estimated or intended. There can be no assurance that such statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers should not place undue reliance on forward-looking statements and forward-looking information. Readers are cautioned that reliance on such information may not be appropriate for other purposes. The Company does not undertake to update any forward-looking statement, forward-looking information or financial outlook that are incorporated by reference herein, except in accordance with applicable securities laws. We seek safe harbor.

Copyright (c) 2025 TheNewswire – All rights reserved.

(TheNewswire)

VANCOUVER September 12, 2025 TheNewswire – Providence Gold Mines Inc. (‘Providence’ or the ‘Company’) is pleased to announce a non brokered Unit Private Placement Financing of up to $250,000 through the issuance of 5,000,000 units oof the Company (each a ‘Unit’) the (‘Private Placement’). Each Unit will consist of one Common Share and one full Warrant exercisable for a period of two years. The Unit is priced at $0.05 for one Common Share in the Capital of the Company (a ‘Common Share’) and one nontransferable full Warrant. Each nontransferable Warrant will entitle the holder to purchase one additional Common Share at a price of $0.05 for a period of 24 months from the date of closing of the Private Placement will be subject to the approval of the TSXV.

All securities issued with respect to the Private Placement will be subject to a four month plus one day hold period from the date of issuance in accordance with applicable securities laws. Closing of the Private Placement is subject to all necessary regulatory approvals. The Company intends to issue the Units pursuant to the prospectus exemptions set out in National Instrument 45-106- Prospectus Exemptions including the accredited investor exemption and family, friends, and business associates’ exemption.

The Company intends to use funds from the net proceeds for Regulatory Fees, sampling and evaluation of the existing potential underground mineralization at the La Dama De Oro , historical ‘Ace in the Hole stope’ , located near surface, geochemical surface survey and administration

As reported previously, an NI 43 101 has been submitted to the TMX V Exchange for review and approval., The Regulators initial review determined that the submission would be treated as a Fundamental Transaction requiring additional information and the Company is responding accordingly.

Property Summary:

Permits for a Bulk Sample, Water, Road Access, Environmental, Plan of Operation, Mill Site have been approved. To date, there has not been any known drilling or modern-day Scientific exploration or identified NI 43 101 resources.

The La Dama de Oro Property is in the Silver Mountain Mining District, within the structurally complex Eastern California Shear Zone and the intersection with the San Andreas Fault Zone. Bedrock geology includes Mesozoic quartz monzonite that intrudes the Jurassic Sidewinder Volcanics. The structural history of the region implies a sequence of compressional and extensional events that reactivated favorably oriented zones of weakness for the circulation of hydrothermal fluids. The main zone of mineralization is hosted by the La Dama de Oro Fault, a shallow northeast-dipping oblique-slip fault.

The mineralization at the property is classified as a structurally controlled, low-sulfidation epithermal gold-silver vein system. Gold and silver mineralization is associated with multi-phase quartz veining, brecciation, and pervasive hydrothermal alteration along the La Dama de Oro Fault. The largest known vein is 4.5 feet at its widest point and remains open to exploration for over 6,000 feet. The gold system has robust potential not just within the La Dama de Oro vein, but as well for additional undiscovered veins along the fault system.

Ronald A. Coombes, President & CEO commented; ‘having all permits in place gives certainty to realize potential future opportunity for production at the La Dama de Oro mine ‘ .

The scientific and technical information contained in this news release has been reviewed and approved by Zachary Black, SME-RM, a Qualified Person as defined under NI 43-101. Mr. Black is a consultant and is independent of Providence Gold Mines Inc.

For more information, please contact Ronald Coombes, President, and CEO directly at

6047242369.

Ronald A. Coombes, President & CE

Phone: 604 724 2369

roombes@providencegold.com

CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING INFORMATION

Neither the OTCQB and or the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

All statements, trend analysis and other information contained in this press release relative to markets about anticipated future events or results constitute forward-looking statements. All statements, other than statements of historical fact, included herein, including, without limitation, statements relating to the permitting process, future production of Providence Gold Mines, budget and timing estimates, the Company’s working capital and financing opportunities and statements regarding the exploration and mineralization potential of the Company’s properties, are forward-looking statements. Forward-looking statements are subject to business and economic risks and uncertainties and other factors that could cause actual results of operations to differ materially from those contained in the forward- looking statements. Important factors that could cause actual results to differ materially from Providence Gold Mines expectations include fluctuations in commodity prices and currency exchange rates; uncertainties relating to interpretation of drill results and the geology, continuity and grade of mineral deposits; the need for cooperation of government agencies and native groups in the exploration and development of properties and the issuance of required permits; the need to obtain additional financing to develop properties and uncertainty as to the availability and terms of future financing; the possibility of delay in exploration or development programs and uncertainty of meeting anticipated program milestones; and uncertainty as to timely availability of permits and other governmental approvals. Forward-looking statements are based on estimates and opinions of management at the date the statements are made. Providence Gold Mines does not undertake any obligation to update forward-looking statements except as required by applicable securities laws. Investors should not place undue reliance on forward-looking statement

Copyright (c) 2025 TheNewswire – All rights reserved.