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Graphite prices have experienced volatility recently due to bottlenecks in demand for electric vehicles.

One major factor experts are watching right now is the trade war between China and the US.

China introduced export restrictions on certain graphite products on December 1, 2023, making it a requirement for Chinese exporters to apply for special permits to ship the material to global markets. In July 2024, the Trump administration in the US announced it would raise tariffs on battery-grade graphite imports from China to 93.5 percent.

Another trend shaping the graphite market in 2025 has been increasing substitution of natural graphite with synthetic in battery anode production; this comes in response to Chinese exports restrictions and US tariffs on natural graphite.

This has led to much lower prices for natural graphite, and against that backdrop, many Canadian graphite stocks have trended down. However, several graphite-focused companies have seen strong performances this year.

Below is a look at the year’s best-performing graphite stocks on the TSXV and CSE; TSX companies were considered, but none made the cut this time. Data was obtained on July 29, 2025, using TradingView’s stock screener, and all companies listed had market caps above C$10 million at that time. Read on to learn more about their work this year.

1. HydroGraph Clean Power (CSE:HG)

Year-to-date gain: 384.21 percent
Market cap: C$282.81 million
Share price: C$0.99

HydroGraph Clean Power produces cost-effective, high-purity graphene, hydrogen and other strategic nanomaterials.

Graphene, a pure carbon material extracted from graphite, has myriad potential applications in industries such as transport, solar cells, medicine, electronics, energy, defense and desalination. HydroGraph has an exclusive license from Kansas State University to produce graphene and hydrogen through the organization’s patented detonation process.

Much of HydroGraph’s news flow in 2025 has centered on strategic partnerships.

Results from a research study conducted with Arizona State University were released in January, demonstrating that the company’s HydroGraph’s Fractal Graphene is well suited for ultra-high-performance concretes and 3D-printed structures. In February, HydroGraph announced a technical collaboration with an unnamed global leader in synthetic fiber manufacturing to assess the potential of its graphene technology in high-performance fiber applications.

The following month, HydroGraph shared the launch of a line of advanced graphene dispersions developed in collaboration with battery materials and testing services company NEI. The products have the potential to be used to produce high-performance electrodes for use in energy storage solutions.

The company signed a letter of intent in April that could lead to a leading North American industrial gas supplier providing it with access to large volumes of high-purity acetylene. This is an essential material in HydroGraph’s patented detonation synthesis process. Acquiring this feedstock will help the firm advance its plans to build a new graphene production facility in Texas with the capacity to produce over 350 metric tons of graphene annually.

HydroGraph launched its Compounding Partner Program in July with the goal of attaining commercial-scale production of its high-performance Fractal Graphene in thermoplastics. According to the company, initial certified partners are testing new formulations in the automotive and packaging sectors.

After trading in a range of C$0.22 to C$0.35 for much of the year, shares of HydroGraph jumped nearly 300 percent in a matter of days to reach a year-to-date high of C$0.99 on July 29.

2. Black Swan Graphene (TSXV:SWAN)

Year-to-date gain: 107.35 percent
Market cap: C$60.02 million
Share price: C$1.41

Black Swan Graphene describes itself as an emerging powerhouse in the bulk graphene business.

The company is a spinout of Mason Resources (TSXV:LLG,OTCQX:MGPHF), which owns the Uatnan graphite project in Québec and holds a 39 percent stake in Black Swan. Graphite from Uatnan is used to supply Black Swan.

UK-based global chemicals manufacturer Thomas Swan & Co. holds a 15 percent interest in Black Swan, and brings a portfolio of patents and intellectual property related to graphene production. Through this partnership, Black Swan is building out a fully integrated supply chain of mine-to-graphene products.

Black Swan’s share price traded sideways for much of the year before benefiting greatly from a summer surge. Shares of Black Swan reached their highest year-to-date price of C$1.52 on July 23.

This followed a series of positive news items concerning progress on increasing commercial output. On June 3, Black Swan announced the installation of an additional production unit at its operational facility in the UK. It is working to more than triple its annual production capacity from 40 metric tons of high-quality graphene to 140 metric tons.

Later in the month, the company signed a non-exclusive distribution and sales agreement with Indian specialty materials and polymers supplier METCO Resources. The agreement will allow METCO to “distribute and promote Black Swan’s graphene nanoplatelets and GEM advanced masterbatch products to customers across India’s industrial, packaging, automotive, and construction sectors,” as per a press release.

Black Swan made another key announcement in the following month. On July 9, the market learned the company had secured a US patent for its breakthrough continuous graphene production process.

3. Focus Graphite Advanced Materials (TSXV:FMS)

Year-to-date gain: 100 percent
Market cap: C$12.26 million
Share price: C$0.135

Focus Graphite Advanced Materials is both a graphite miner and a battery technology company. Its wholly owned flagship Lac Knife high-grade crystalline flake graphite project is located in Northeastern Québec.

With a completed feasibility study, Lac Knife is one of North America’s most advanced graphite deposits. The company also holds Lac Tétépisca, the highest-purity graphite project in Québec.

In terms of battery technologies, Focus Graphite has a patent-pending proprietary silicone-enhanced spheroidized graphite technology that is designed to enhance battery performance and efficiency.

In late May, definition drilling at Lac Tétépisca led to an extension of the strike length of the mineralized zone to over 6 kilometers, while preliminary metallurgical testing confirmed the quality of the project’s flake graphite.

In mid-June, the company said thermal purification testing on Lac Knife flake graphite completed by American Energy Technologies Company had resulted in refined concentrate to a purity level of 99.999 percent carbon.

“This milestone underscores Focus Graphite’s potential to supply ultra-high-purity graphite material for nuclear energy applications, a market historically dominated by synthetic graphite and limited to a small cohort of qualifying producers,” states the company’s press release.

Shares of Focus Graphite hit their highest year-to-date value of C$0.17 on June 17.

Securities Disclosure: I, Melissa Pistilli, hold no direct investment interest in any company mentioned in this article.

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The price of zinc was on the rise in 2024, but this year has been a different story. The metal’s value has trended down for most of 2025 on the back of increased supply and weakening demand.

Many base metals have taken hit from lagging demand in recent years due to sticky inflation and higher interest rates, and zinc is no exception. Zinc supply has also faced pressure from higher mining and refining costs, causing some major zinc mines and smelters to suspend operations, with more possible if the current economic situation continues.

With its important role in the steel manufacturing process, the zinc market is heavily influenced by international trade. One area of support in the last few months has been turmoil caused by the US-China trade war and tariff threats .

Data was gathered on July 30, 2025, using TradingView’s stock screener, and only zinc stocks with market caps greater than C$50 million at that time were considered. Read on to learn more about their operations and plans.

1. Teck Resources (TSX:TECK.A,TSX:TECK.B)

Market cap: C$22.01 billion
Share price: C$45.04

Teck Resources is a major global polymetallic miner, as well as one of the world’s top zinc producers.

The Vancouver-headquartered company produced 615,900 metric tons (MT) of zinc in concentrate in 2024, with 555,600 MT coming from its Red Dog zinc mine in Alaska. The remaining 60,300 MT came from Teck’s 22.5 percent share of zinc production from the Peru-based Antamina copper-zinc mine.

Teck’s total 2025 production guidance for the base metal is set in a range of 525,000 to 575,000 MT. As of June 30, the company’s zinc production for the year totaled 384,000 MT.

In addition to the sites mentioned, Teck owns the Trail operations, which it describes as ‘one of the world’s largest fully integrated zinc and lead smelting and refining complexes.’ Located in BC, Canada, the Trail operations produced 256,000 MT of refined zinc in 2024, with 190,000 to 230,000 MT of the material expected in 2025.

Teck pays a quarterly dividend. On September 29, it will pay out a dividend of C$0.125 per share.

2. Fireweed Metals (TSXV:FWZ)

Market cap: C$485.11 million
Share price: C$2.32

Fireweed Metals is a critical metals company whose flagship Macmillan Pass zinc project is located in Canada’s Yukon. In 2023, the company acquired the Gayna River zinc project in the Northwest Territories, as well as the Mactung tungsten project, which is adjacent to Macmillan Pass and straddles the border between Yukon and the Northwest Territories. According to Fireweed, Mactung ‘hosts the world’s largest high-grade tungsten deposit.’

Even with these new assets, the company still has a strong focus on Macmillan Pass. In fact, in November 2023, the Fireweed team, led by Dr. Jack Milton, the firm’s vice president of geology, received the Association for Mineral Exploration’s H.H. “Spud” Huestis Award for its work at the Macmillan Pass property.

Fireweed’s best drill intersection to date from Macmillan Pass’ Boundary zone includes 143.95 meters true width at 14.45 percent zinc, including 28.71 meters at 25.52 percent zinc. In September 2024, after its largest regional exploration campaign ever at Macmillan Pass, the company released an updated resource estimate for the Tom and Jason deposits, as well as inaugural resource estimates for the Boundary zone and End zone deposits.

Fireweed launched its 2025 field program in early June, saying it will include 12,000 meters of diamond drilling at Macmillan Pass. The work will target ‘both high-priority regional prospects and step-outs around known zinc-lead-silver-gallium-germanium deposits,’ according to a press release.

3. Trilogy Metals (TSX:TMQ)

Market cap: C$405.68 million
Share price: C$2.47

Trilogy Metals is focused primarily on copper, zinc and cobalt at its Alaskan Upper Kobuk projects, which are held by Ambler Metals, a joint venture operating company owned equally by Trilogy and South32 (ASX:S32,OTC Pink:SHTLF).

Its most advanced zinc project is the Arctic copper-zinc-lead-gold-silver volcanogenic massive sulfide project, which is in the feasibility stage and has proven and probable reserves of 43.44 million MT grading 3.12 percent zinc.

In addition, early stage 2023 field work at the company’s wholly owned Helpmejack project in Alaska’s Ambler schist belt outlined two target areas prospective for volcanogenic massive sulfide and shale-hosted zinc deposits.

Trilogy had been focusing on improving access to the region with its Amber Access project, but it was rejected by the US Bureau of Land Management under the Biden administration in June 2024 due to the impact the proposed road could have on the environment and communities in the region, which have seen little development.

However, under the Trump administration, a series of executive and secretarial orders focusing on developing Alaska’s natural resources have been enacted that could reverse this decision.

“Recent actions taken by President Donald Trump and Interior Secretary Doug Burgum signal a positive path forward for the Ambler Road,’ Trilogy Metals President and CEO Tony Giardini said. ‘This transportation corridor is crucial not only for providing access to the minerals that are vital to U.S. national security and prosperity, but also for much-needed economic growth and job creation in Alaska. Trilogy Metals is committed to working with all stakeholders on progressing the road, to unlock the vast natural resource potential of the Ambler Mining District.”

4. Emerita Resources (TSXV:EMO)

Market cap: C$317.02 million
Share price: C$1.20

Emerita Resources has a portfolio of high-grade, large-scale polymetallic projects covering more than 26,000 combined hectares in Spain’s Iberian Pyrite Belt. The company’s flagship asset is the Iberian Belt West project, which hosts three massive sulfide deposits: La Infanta, La Romanera and El Cura.

Emerita released a resource estimate for Iberian Belt West in May 2023. It finished environmental baseline studies the following month, and completed supporting documentation for its mining license application in December 2023.

In July 2024, the Andalusian government granted Iberian Belt West a declaration of strategic interest, which will streamline the process of moving the project through development.

Phase 2 metallurgical testing results for the La Romanera and La Infanta deposits released in late 2024 show that commercial-grade copper, lead and zinc concentrates can be obtained from both deposits.

In March of this year, Emerita announced an updated resource estimate for Iberian Belt West, showing a 35 percent increase to the total indicated mineral resource tonnage and a 44 percent increase in total inferred mineral resource tonnage. Also this year, Emerita made the cut for the latest TSX Venture 50 list.

Securities Disclosure: I, Melissa Pistilli, hold no direct investment interest in any company mentioned in this article.

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Here’s a quick recap of the crypto landscape for Wednesday (August 13) as of 9:00 p.m. UTC.

Get the latest insights on Bitcoin, Ethereum and altcoins, along with a round-up of key cryptocurrency market news.

Bitcoin and Ethereum price update

Bitcoin (BTC) was priced at US$122,444, up by 2.6 percent over the last 24 hours, and its highest valuation of the day. It briefly dropped to its lowest valuation of $120,414 shortly after the opening bell.

Bitcoin has found itself at the crossroads of macroeconomic data, political influence and shifting capital flows. Inflation statistics and central bank dynamics have introduced caution, while stablecoin activity and institutional appetite are hinting at a redistribution into altcoins.

Bitcoin price performance, August 13, 2025.

Chart via TradingView.

Meanwhile, Ethereum (ETH) continued to rally, up by 4.5 percent to US$4,716.60. The cryptocurrency’s lowest valuation on Wednesday was US$4,638.43, and its highest was US$4,738.59.

Glassnode notes that ETH is a bellwether for altcoins, and its current move as capital continues to flow into exchange-traded funds suggests further upside. In an X post on Wednesday, Charles Edwards, founder of crypto quantitative digital asset fund Capriole Investments, shared data showing that 75 percent of Coinbase Global’s (NASDAQ:COIN) volume came from institutional players on Tuesday (August 12).

He pointed to the outlook for interest rates following the release of July inflation data.

Altcoin price update

  • Solana (SOL) was priced at US$200.74, up by 6.1 percent over 24 hours, and its highest valuation of the day. Its lowest valuation was US$195.81.
  • XRP was trading for US$3.27, up 0.1 percent in the past 24 hours and at its highest valuation of the day. Its lowest was US$3.24.
  • Sui (SUI) was trading at US$3.99, up by 2.3 percent over the past 24 hours, and its highest valuation of the day. Its lowest level was US$3.93.
  • Cardano (ADA) was trading at US$0.8827, up by 4.6 percent over 24 hours, and its highest valuation on Wednesday. Its lowest was US$0.8660.

Today’s crypto news to know

World Liberty Financial sets up US$1.5 billion crypto treasury

World Liberty Financial, a digital asset venture backed by US President Donald Trump and his sons, has announced plans to establish a US$1.5 billion “crypto treasury” in partnership with ALT5 Sigma (NASDAQ:ALTS).

Under the deal, ALT5 will raise US$1.5 billion through the sale of its own shares. The funds will go toward the purchase of World Liberty’s in-house token, $WLFI, and will also be used to set up a crypto treasury, settle litigation, pay down debt and for other corporate uses. It will ultimately hold about 7.5 percent of $WLFI tokens.

Unnamed institutional investors and venture capital firms participated in the share sale. Crypto treasury models have grown in popularity this year amid a friendlier US regulatory stance under the Trump administration.

The project’s leadership is heavily tied to the Trump family, with Trump himself listed as “co-founder emeritus,” and Eric, Donald Jr. and Barron Trump holding co-founder titles.

As part of the arrangement, Eric Trump will join ALT5’s board and Zach Witkoff will serve as its chair.

Bullish shares surge on NYSE debut

Bullish (NYSE:BLSH), the parent company of Bullish Exchange and CoinDesk, began trading on the New York Stock Exchange on Wednesday. Shares were priced at US$37 each, an increase from an earlier target of US$33, with 30 million on offer to raise US$1.1 billion and value the company at nearly US$5.4 billion.

Shares surged as much as 218 percent to reach US$118 on trading volume of roughly 38 million shares, before pulling back to close at US$70.65. The initial public offering pushed the company’s market cap above US$10 billion.

Banking groups push for stablecoin loophole closure

US banking groups, led by the Bank Policy Institute (BPI), are urging Congress to close a loophole that allows stablecoin issuers to indirectly offer yields through affiliates. They argue that while new stablecoin laws prevent issuers from directly offering yield, they don’t prohibit crypto exchanges or affiliated businesses from doing so.

The groups contend that this circumvents the law and could lead to a US$6.6 trillion outflow of deposits from traditional banks, potentially disrupting credit flow to American businesses and families.

Banks are concerned that yield-bearing stablecoins undermine their ability to attract deposits, which are crucial for backing loans. The offering of yield is a significant marketing draw for stablecoins, with some, like USDC, already rewarding holders on exchanges such as Kraken and Coinbase (NASDAQ:COIN).

Safe harbor programs proposed for DeFi

In a Wednesday letter, Andreessen Horowitz (a16z) and the DeFi Education Fund asked the US Securities and Exchange Commission (SEC) and Hester Peirce, head of the commission’s Crypto Task Force, to set up a safe harbor program from broker-dealer registration requirements for non-fungible token (NFT) and DeFi applications.

The group said the letter was a follow up to Trump’s Working Group on Digital Assets, which called on the SEC to give certain DeFi service providers relief from registration provisions under the Exchange Act, specifically those related to broker-dealers, exchanges and clearing agencies. SEC Chair Paul Atkins also directed staff to update “antiquated agency rules and regulations” for certain crypto and blockchain applications in July.

To avoid enforcement actions, a safe harbor provision would exempt some companies that offer crypto-related products and services from enforcement actions. a16z has sent two previous letters to the commission this year recommending safe harbors for NFTs, airdrops and network tokens.

Securities Disclosure: I, Giann Liguid, hold no direct investment interest in any company mentioned in this article.

Securities Disclosure: I, Meagen Seatter, hold no direct investment interest in any company mentioned in this article.

This post appeared first on investingnews.com

Keith Weiner, founder and CEO of Monetary Metals, discusses gold and silver’s performance so far this year and shares his outlook for the rest of 2025.

He also explains what makes today’s gold bull market different than those seen in prior years.

Securities Disclosure: I, Charlotte McLeod, hold no direct investment interest in any company mentioned in this article.

This post appeared first on investingnews.com

(TheNewswire)

TORONTO, ON, August 13, 2025 TheNewswire – Silver Crown Royalties Inc. ( Cboe: SCRI,OTC:SLCRF; OTCQX: SLCRF; FRA: QS0) ( ‘Silver Crown’ or the ‘Company’ ) is pleased to announce that, further to its press release dated August 7, 2025, it has closed the acquisition of a royalty on 90% of the cash equivalent of silver produced each quarter from the past producing Scotia Mine (the ‘Silver Royalty’ ) with EDM Resources Inc. ( TSX-V: EDM; FSE: P3Z) ( ‘EDM’ ). The Silver Royalty provides for minimum of the cash equivalent of 7,000 ounces per year for 10 years starting at commercial production on the Scotia Mine. SCRi paid $250,000 in cash at closing and issued 60,000 units (‘ Units ‘) to EDM per Unit at a deemed value of C$10.00, with each Unit consisting of a common share in the capital of SCRi (‘ Common Share ‘) and one warrant exercisable into an additional Common Share at a price of C$13.00 for a period of 36 months following the date hereof. SCRi must pay EDM an additional C$250,000 cash payment following the date hereof as deferred consideration for the Silver Royalty.

ABOUT EDM RESOURCES INC.

EDM Resources Inc. (‘EDM’) ( TSX-V: EDM; FSE: P3Z) is a Canadian exploration and mining company that has full ownership of the Scotia Mine and related facilities near Halifax, Nova Scotia. Through its wholly owned subsidiary, EDM also holds several prospective exploration licenses near its Scotia Mine and in the surrounding regions of Nova Scotia .

ABOUT Silver Crown Royalties INC.

Founded by seasoned industry professionals, Silver Crown Royalties ( Cboe: SCRI | OTCQX: SLCRF | FRA: QS0) is a publicly traded silver royalty company dedicated to generating free cash flow. Silver Crown (SCRi) currently holds five silver royalties. Its business model offers investors exposure to precious metals, providing a natural hedge against currency devaluation while mitigating the adverse effects of production-related cost inflation. SCRi strives to minimize the economic burden on mining projects while simultaneously maximizing shareholder returns. For further information, please contact:

Silver Crown Royalties Inc.

Peter Bures, Chairman and CEO

Telephone: (416) 481-1744

Email: pbures@silvercrownroyalties.com

FORWARD-LOOKING STATEMENTS

This release contains certain ‘forward looking statements’ and certain ‘forward-looking information’ as defined under applicable Canadian and U.S. securities laws. Forward-looking statements and information can generally be identified by the use of forward-looking terminology such as ‘may’, ‘will’, ‘should’, ‘expect’, ‘intend’, ‘estimate’, ‘anticipate’, ‘believe’, ‘continue’, ‘plans’ or similar terminology. The forward-looking information contained herein is provided for the purpose of assisting readers in understanding management’s current expectations and plans relating to the future. Readers are cautioned that such information may not be appropriate for other purposes. Forward-looking statements and information include, but are not limited to, SCRi must pay EDM an additional C$250,000 cash payment following the date hereof as deferred consideration for the Silver Royalty . Forward-looking statements and information are based on forecasts of future results, estimates of amounts not yet determinable and assumptions that, while believed by management to be reasonable, are inherently subject to significant business, economic and competitive uncertainties and contingencies. Forward-looking information is subject to known and unknown risks, uncertainties and other factors that may cause the actual actions, events or results to be materially different from those expressed or implied by such forward-looking information, including but not limited to: the impact of general business and economic conditions; the absence of control over mining operations from which SCRi will purchase gold and other metals or from which it will receive royalty payments and risks related to those mining operations, including risks related to international operations, government and environmental regulation, delays in mine construction and operations, actual results of mining and current exploration activities, conclusions of economic evaluations and changes in project parameters as plans continue to be refined; accidents, equipment breakdowns, title matters, labor disputes or other unanticipated difficulties or interruptions in operations; SCRi’s ability to enter into definitive agreements and close proposed royalty transactions; the inherent uncertainties related to the valuations ascribed by SCRi to its royalty interests; problems inherent to the marketability of gold and other metals; the inherent uncertainty of production and cost estimates and the potential for unexpected costs and expenses; industry conditions, including fluctuations in the price of the primary commodities mined at such operations, fluctuations in foreign exchange rates and fluctuations in interest rates; government entities interpreting existing tax legislation or enacting new tax legislation in a way which adversely affects SCRi; stock market volatility; regulatory restrictions; liability, competition, the potential impact of epidemics, pandemics or other public health crises on SCRi’s business, operations and financial condition, loss of key employees. SCRi has attempted to identify important factors that could cause actual results to differ materially from those contained in forward-looking statements, there may be other factors that cause results not to be as anticipated, estimated or intended. There can be no assurance that such statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, readers are advised not to place undue reliance on forward-looking statements or information. SCRi undertakes no obligation to update forward-looking information except as required by applicable law. Such forward-looking information represents management’s best judgment based on information currently available.

This document does not constitute an offer to sell, or a solicitation of an offer to buy, securities of the Company in Canada, the United States or any other jurisdiction. Any such offer to sell or solicitation of an offer to buy the securities described herein will be made only pursuant to subscription documentation between the Company and prospective purchasers. Any such offering will be made in reliance upon exemptions from the prospectus and registration requirements under applicable securities laws, pursuant to a subscription agreement to be entered into by the Company and prospective investors. There can be no assurance that forward-looking statements will prove to be accurate, as actual results and future events could differ materially from those anticipated in such statements. Accordingly, the reader is cautioned not to place undue reliance on forward-looking statements.

CBOE CANADA DOES NOT ACCEPT RESPONSIBILITY FOR THE ADEQUACY OR ACCURACY OF THIS NEWS RELEASE.

Copyright (c) 2025 TheNewswire – All rights reserved.

News Provided by TheNewsWire via QuoteMedia

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Generative artificial intelligence (AI) has helped a group of scientists identify five new materials that could power the next wave of batteries without relying on lithium.

The study, published on June 26 in Cell Reports Physical Science, focuses on materials that could enable multivalent-ion batteries — a technology long touted for its potential, but hindered by practical challenges.

The lithium problem for batteries

Lithium dominates in batteries used in everything from smartphones to electric vehicles, but faces challenges — it is costly to extract, geographically concentrated and comes with environmental and geopolitical concerns.

As global demand for batteries surges, researchers are racing to find viable alternatives that are both abundant and efficient. Multivalent-ion batteries offer one potential path forward. Unlike lithium-ion batteries, which carry a single positive charge, multivalent-ion batteries using materials like magnesium or zinc carry two or three.

In theory, this means that they can pack more energy into the same space. However, their larger size and stronger charge make it difficult for them to move through standard battery materials.

“One of the biggest hurdles wasn’t a lack of promising battery chemistries — it was the sheer impossibility of testing millions of material combinations,” said lead author Dibakar Datta, a professor of mechanical and industrial engineering at the New Jersey Institute of Technology. “We turned to generative AI as a fast, systematic way to sift through that vast landscape and spot the few structures that could truly make multivalent batteries practical.”

To tackle the challenge, Datta’s team developed a “dual AI” system. The first part, a crystal diffusion variational autoencoder (CDVAE), was trained on vast datasets of known crystal structures. It could generate entirely new porous transition metal oxides, a class of material known for its structural flexibility and ionic conductivity.

The second part was a fine-tuned large language model (LLM) designed to narrow the list.

It focused on materials closest to thermodynamic stability, a critical factor in determining whether a compound can realistically be made and used in the real world.

The CDVAE cast a wide net, creating thousands of hypothetical structures with large, open channels. The LLM then acted as a filter, selecting only those most likely to hold up under actual manufacturing and operational conditions.

Five new battery candidates

“Our AI tools dramatically accelerated the discovery process, which uncovered five entirely new porous transition metal oxide structures that show remarkable promise,” Datta said.

These structures, the study suggests, offer unusually large pathways for ion movement, a crucial step toward making multivalent batteries that charge quickly and last for long periods of time. Quantum mechanical simulations and stability tests confirmed that the materials should be both synthetically feasible and structurally sound.

The five compounds now move to the next stage — experimental synthesis in collaboration with partner laboratories. If successful, they could be incorporated into prototype batteries and eventually scaled for commercial production.

Traditional materials research is often a painstaking, years-long process of hypothesis, synthesis and testing.

By contrast, AI can rapidly explore enormous “material spaces” that would be impossible for humans to search manually, flagging only the most promising candidates for further investigation.

What it means for the batteries of tomorrow

Multivalent-ion batteries have been studied for decades, yet few have reached commercial readiness because the necessary materials either didn’t conduct ions well enough or degraded too quickly.

By using AI to overcome that bottleneck, the research team hopes to accelerate not just battery chemistry, but also the infrastructure needed to support electrification on a global scale.

However, the five materials identified by Datta’s team aren’t ready to replace lithium tomorrow. They still need to be synthesized, tested in lab-scale batteries and proven to perform under real-world conditions.

Safety, scalability and cost effectiveness all remain open questions.

Still, the study’s authors argue that their AI framework has already proven its value by shrinking what could have been a decades-long search into a matter of months.

“This is more than just discovering new battery materials — it’s about establishing a rapid, scalable method to explore any advanced materials, from electronics to clean energy solutions, without extensive trial and error,” Datta added.

Securities Disclosure: I, Giann Liguid, hold no direct investment interest in any company mentioned in this article.

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Lithium, a naturally occurring trace element in the brain, may be able to unlock a key medical mystery: why some people develop Alzheimer’s disease and others don’t, despite similar brain changes.

In a recently published study, scientists at Harvard Medical School state that lithium not only exists in the human brain at biologically meaningful levels, but also appears to protect against neurodegeneration.

Additionally, their work shows that lithium supports the function of all major brain cell types.

The decade-long study drew on mouse experiments and analyses of human brain and blood samples across the spectrum of cognitive health. The Harvard team discovered that as amyloid beta, the sticky protein associated with Alzheimer’s, begins to accumulate, it binds to lithium and depletes its availability in the brain. This drop in lithium impairs neurons, glial cells and other brain structures, accelerating memory loss and disease progression.

“The idea that lithium deficiency could be a cause of Alzheimer’s disease is new and suggests a different therapeutic approach,” said Bruce Yankner, who is the senior author of the study.

Yankner, a professor of genetics and neurology at Harvard Medical School who in the 1990s was the first to show that amyloid beta is toxic to nerve cells, said the new findings open the door to treatments that address the disease in its entirety, rather than targeting single features like amyloid plaques or tau tangles.

To explore this possibility, researchers screened for lithium compounds that could evade capture by amyloid beta.

They identified lithium orotate as the most promising candidate. In mice, the compound reversed Alzheimer’s-like brain changes, prevented cell damage and restored memory, even in animals with advanced disease.

Crucially, the effective dose was about one-thousandth of that used in psychiatric treatments, avoiding the toxicity risk that has hampered lithium’s clinical use in older patients.

“You have to be careful about extrapolating from mouse models, and you never know until you try it in a controlled human clinical trial,” Yankner cautioned. “But so far the results are very encouraging.”

The path to these findings began with access to an unusually rich source of brain tissue.

Working with the Rush Memory and Aging Project in Chicago, the team examined postmortem samples from thousands of donors, from cognitively healthy individuals to those with mild cognitive impairment and full-blown Alzheimer’s.

Using advanced mass spectrometry, they measured trace levels of about 30 metals. Lithium stood out as the only one whose levels dropped sharply at the earliest stages of memory loss.

The pattern matched earlier population studies linking higher environmental lithium levels, including in drinking water, to lower dementia rates. But unlike those correlations, the Harvard team directly measured brain lithium and established a normal range for healthy individuals who had never taken lithium as medication.

“Lithium turns out to be like other nutrients we get from the environment, such as iron and vitamin C,” Yankner said. “It’s the first time anyone’s shown that lithium exists at a natural level that’s biologically meaningful without giving it as a drug.”

To test whether this deficiency was more than an association, the researchers fed healthy mice a lithium-restricted diet, lowering brain lithium to levels seen in Alzheimer’s patients.

The animals developed brain inflammation, lost connections between neurons and showed cognitive decline; however, replenishing them with lithium orotate reversed these changes. What’s more, mice given the compound from early adulthood were protected from developing Alzheimer’s-like symptoms altogether.

The findings raise several possibilities. Measuring lithium levels in blood could become a tool for early screening, identifying people at risk before symptoms emerge. Furthermore, amyloid-evading lithium compounds could be tested as preventive or therapeutic agents, potentially altering the disease course more fundamentally than existing drugs.

For now, researchers stress that no one should self-medicate with lithium supplements.

The team emphasized that the safety and efficacy of lithium orotate in humans remain unproven, and clinical trials will be needed to determine whether the dramatic benefits seen in mice translate to people.

Securities Disclosure: I, Giann Liguid, hold no direct investment interest in any company mentioned in this article.

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